JPS6151737B2 - - Google Patents
Info
- Publication number
- JPS6151737B2 JPS6151737B2 JP53106850A JP10685078A JPS6151737B2 JP S6151737 B2 JPS6151737 B2 JP S6151737B2 JP 53106850 A JP53106850 A JP 53106850A JP 10685078 A JP10685078 A JP 10685078A JP S6151737 B2 JPS6151737 B2 JP S6151737B2
- Authority
- JP
- Japan
- Prior art keywords
- layer
- chemical analysis
- reagent
- multilayer chemical
- liquid sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004458 analytical method Methods 0.000 claims description 126
- 239000000463 material Substances 0.000 claims description 112
- 239000000126 substance Substances 0.000 claims description 106
- 239000003153 chemical reaction reagent Substances 0.000 claims description 79
- 239000007788 liquid Substances 0.000 claims description 51
- 238000003892 spreading Methods 0.000 claims description 28
- 230000007480 spreading Effects 0.000 claims description 28
- 238000011161 development Methods 0.000 claims description 20
- 238000009825 accumulation Methods 0.000 claims description 18
- 239000000523 sample Substances 0.000 description 52
- 238000000034 method Methods 0.000 description 25
- 238000000151 deposition Methods 0.000 description 13
- 210000004369 blood Anatomy 0.000 description 10
- 239000008280 blood Substances 0.000 description 10
- 230000008021 deposition Effects 0.000 description 8
- 239000000306 component Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 238000004445 quantitative analysis Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 238000004040 coloring Methods 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- -1 polyethylene terephthalate Polymers 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000004078 waterproofing Methods 0.000 description 2
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 229930185605 Bisphenol Natural products 0.000 description 1
- 229920008347 Cellulose acetate propionate Polymers 0.000 description 1
- 229920001747 Cellulose diacetate Polymers 0.000 description 1
- 229920002284 Cellulose triacetate Polymers 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 description 1
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920006217 cellulose acetate butyrate Polymers 0.000 description 1
- 238000009614 chemical analysis method Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000005137 deposition process Methods 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 201000003373 familial cold autoinflammatory syndrome 3 Diseases 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 239000000123 paper Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000002940 repellent Effects 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/525—Multi-layer analytical elements
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10685078A JPS5533651A (en) | 1978-08-31 | 1978-08-31 | Laminated plate of multi-layered chemical analysis material and using method thereof |
| DE19792934760 DE2934760A1 (de) | 1978-08-31 | 1979-08-28 | Integriertes material fuer die chemische analyse und verfahren zu dessen anwendung |
| US06/071,618 US4270920A (en) | 1978-08-31 | 1979-08-31 | Integrated material for chemical analysis and a method of using the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10685078A JPS5533651A (en) | 1978-08-31 | 1978-08-31 | Laminated plate of multi-layered chemical analysis material and using method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5533651A JPS5533651A (en) | 1980-03-08 |
| JPS6151737B2 true JPS6151737B2 (en]) | 1986-11-10 |
Family
ID=14444092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10685078A Granted JPS5533651A (en) | 1978-08-31 | 1978-08-31 | Laminated plate of multi-layered chemical analysis material and using method thereof |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4270920A (en]) |
| JP (1) | JPS5533651A (en]) |
| DE (1) | DE2934760A1 (en]) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015161656A (ja) * | 2014-02-28 | 2015-09-07 | 公立大学法人奈良県立医科大学 | 被検液物性値の検査用具 |
| WO2021220730A1 (ja) * | 2020-04-30 | 2021-11-04 | ウシオ電機株式会社 | 成分測定方法および成分測定用ストリップ |
| WO2023162095A1 (ja) * | 2022-02-24 | 2023-08-31 | セルスペクト株式会社 | 血液検査デバイス |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5670460A (en) * | 1979-11-13 | 1981-06-12 | Fuji Photo Film Co Ltd | Multilayer chemical analysis material for analysis of water liquid |
| US4323536A (en) * | 1980-02-06 | 1982-04-06 | Eastman Kodak Company | Multi-analyte test device |
| DE3029579C2 (de) * | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| JPH0122135Y2 (en]) * | 1980-08-25 | 1989-06-29 | ||
| SE427389B (sv) * | 1981-03-02 | 1983-03-28 | Alfa Laval Ab | Indikator innefattande en berare och ett reaktionssystem |
| JPS5977356A (ja) * | 1982-06-30 | 1984-05-02 | Fuji Photo Film Co Ltd | 螢光アツセイ用多層分析要素およびそれを用いる螢光アツセイ法 |
| USRE34405E (en) * | 1983-08-01 | 1993-10-12 | Abbott Laboratories | Determination of analytes in particle-containing medium |
| JPH0736012B2 (ja) * | 1984-10-05 | 1995-04-19 | テルモ株式会社 | 試験片 |
| US4857271A (en) | 1985-02-07 | 1989-08-15 | Eastman Kodak Company | Reducible compounds and analytical compositions, elements and methods utilizing same |
| US4678757A (en) * | 1985-04-11 | 1987-07-07 | Smithkline Diagnostics, Inc. | Device and method for whole blood separation and analysis |
| JPS61262661A (ja) * | 1985-05-16 | 1986-11-20 | Konishiroku Photo Ind Co Ltd | 生化学分析ユニツト |
| US4623461A (en) * | 1985-05-31 | 1986-11-18 | Murex Corporation | Transverse flow diagnostic device |
| US4857453A (en) * | 1987-04-07 | 1989-08-15 | Syntex (U.S.A.) Inc. | Immunoassay device |
| US5256372A (en) * | 1987-11-06 | 1993-10-26 | Idexx Corporation | Dipstick test device including a removable filter assembly |
| DE3889885T2 (de) * | 1987-12-23 | 1994-12-15 | Abbott Lab | Vorrichtung zur Agglutinierungsreaktion. |
| US4963325A (en) * | 1988-05-06 | 1990-10-16 | Hygeia Sciences, Inc. | Swab expressor immunoassay device |
| JPH0715427U (ja) * | 1990-12-29 | 1995-03-14 | デルタ工業株式会社 | 自動車用シート |
| DE4217733A1 (de) * | 1992-05-29 | 1993-12-02 | Boehringer Mannheim Gmbh | Testträger zur Analytbestimmung sowie Verfahren zu dessen Herstellung |
| US5707818A (en) * | 1994-12-13 | 1998-01-13 | Bsi Corporation | Device and method for simultaneously performing multiple competitive immunoassays |
| US5981298A (en) * | 1995-12-13 | 1999-11-09 | Surmodics, Inc. | Immunoassay device and method |
| AU6035299A (en) * | 1998-09-09 | 2000-03-27 | Amira Medical | Interstitial fluid methods and devices for determination of an analyte in the body |
| US6251083B1 (en) | 1999-09-07 | 2001-06-26 | Amira Medical | Interstitial fluid methods and devices for determination of an analyte in the body |
| US7816090B2 (en) * | 2007-01-10 | 2010-10-19 | Ortho-Clinical Diagnostics, Inc. | Multiple immunochemistry assays on an element |
| US9903858B2 (en) | 2014-07-23 | 2018-02-27 | Ortho-Clinical Diagnostics, Inc. | Multiplexing with single sample metering event to increase throughput |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3006735A (en) * | 1959-09-22 | 1961-10-31 | Morton Salt Co | Quick-dip indicator |
| US3139328A (en) * | 1960-07-21 | 1964-06-30 | Sun Oil Co | Indicator paper |
| DE2332760C3 (de) * | 1972-06-30 | 1982-03-04 | Eastman Kodak Co., 14650 Rochester, N.Y. | Material für die quantitative spektrophotometrische Analyse einer Flüssigkeit |
| US4046512A (en) * | 1976-02-20 | 1977-09-06 | Westinghouse Electric Corporation | Device for indicating overheating in generators |
| US4050898A (en) * | 1976-04-26 | 1977-09-27 | Eastman Kodak Company | Integral analytical element |
-
1978
- 1978-08-31 JP JP10685078A patent/JPS5533651A/ja active Granted
-
1979
- 1979-08-28 DE DE19792934760 patent/DE2934760A1/de active Granted
- 1979-08-31 US US06/071,618 patent/US4270920A/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015161656A (ja) * | 2014-02-28 | 2015-09-07 | 公立大学法人奈良県立医科大学 | 被検液物性値の検査用具 |
| WO2021220730A1 (ja) * | 2020-04-30 | 2021-11-04 | ウシオ電機株式会社 | 成分測定方法および成分測定用ストリップ |
| JP2021177169A (ja) * | 2020-04-30 | 2021-11-11 | ウシオ電機株式会社 | 成分測定方法および成分測定用ストリップ |
| WO2023162095A1 (ja) * | 2022-02-24 | 2023-08-31 | セルスペクト株式会社 | 血液検査デバイス |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2934760A1 (de) | 1980-03-13 |
| JPS5533651A (en) | 1980-03-08 |
| US4270920A (en) | 1981-06-02 |
| DE2934760C2 (en]) | 1988-05-05 |
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